One of the significant weaknesses I see in many player's games is the overplaying of draws against a made hand, especially when a pot is small. This is a flaw which I see in the very best of the 5-10 game to the ok players in the 2-4. Because they "know" that they are probably no worse than 6:4 dogs, and they are getting 2:1 on the action, they then proceed to lump in their stack against what surely must be a made hand. But these can be very -EV plays. Perhaps an example will make it clear. In a 2-4 game, unraised pot, I flop top trips on a 2TJ rainbow flop. My opponent bets the flop, I raise, he reraises, repeat till his $317 stack has gone :-)
So what has happened here, EV-wise? He has put in $317 to win $341 strange. This is 1.08 to 1 money odds. His "wrap" was just the top cards AKQ and I had a blocker in the 9. So his chance of winning was 1.67 to 1. The whole play has a -EV of about 20% and continually playing like this will soon send him to the poker hospital.
So how do you play it then?
Just call. You will have the right odds, or near enough in most cases, to call a blank turn. And if it pairs up you can pass. Also if you do hit the turn with your draw, you can bet and make him potentially make a very bad call to fill up.
Aggression is good, but not when it drives you to bankroll extinction.